Thursday, July 20, 2017

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Parafluorofentanyl

Parafluorofentanyl (4-Fluorofentanyl) is an opioid analgesic being an analogue of fentanyldeveloped by Janssen Pharmaceutica in the 1960s.[1]
Parafluorofentanyl
Parafluorofentanyl.svg
Clinical data
ATC code
  • none
Legal status
Legal status
Identifiers
CAS Number
PubChemCID
ChemSpider
UNII
ChEBI
Chemical and physical data
FormulaC22H27FN2O
Molar mass354.461 g/mol
3D model (JSmol)
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4-Fluorofentanyl was sold briefly on the US black market in the early 1980s,[citation needed] before the introduction of the Federal Analog Act which for the first time attempted to control entire families of drugs based on their structural similarity rather than scheduling each drug individually as they appeared.[2] 4-Fluorofentanyl is made with the same synthetic route as fentanyl, but by substituting para-fluoroaniline for aniline in the synthesis.[3]
Side effects of fentanyl analogs are similar to those of fentanyl itself, which include itchingnausea and potentially serious respiratory depression, which can be life-threatening. Fentanyl analogs have killed hundreds of people throughout Europe and the former Soviet republics since the most recent resurgence in use began in Estonia in the early 2000s, and novel derivatives continue to appear.[4]

See also


Ms-13 the honest doctors
when the say kill they mean what they say

health insurance dishonest killing by placing money over useful art snd scirnce like thst of fsustmsnlab.org.org   
Edit

ReferencesEdit

  1. ^ US patent 3164600
  2. ^ Henderson, G. L. (1988). "Designer Drugs: Past History and Future Prospects". Journal of Forensic Sciences33 (2): 569–575. PMID 3286815.
  3. ^ Ulens, C.; Van Boven, M.; Daenens, P.; Tytgat, J. (2000). "Interaction of p-Fluorofentanyl on Cloned Human Opioid Receptors and Exploration of the Role of Trp-318 and His-319 in μ-Opioid Receptor Selectivity" (pdf)The Journal of Pharmacology and Experimental Therapeutics294 (3): 1024–1033. PMID 10945855.
  4. ^ Jane Mounteney; Isabelle Giraudon; Gleb Denissov; Paul Griffiths (July 2015). "Fentanyls: Are we missing the signs? Highly potent and on the rise in Europe."The international journal of drug policy26 (7): 626–631. PMID 25976511doi:10.1016/j.drugpo.2015.04.003.

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