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Janine Austin Clayton, M.D.

Follow Dr. Clayton on Twitter at @JanineClaytonMD  

Janine Austin Clayton, M.D., was appointed Associate Director for Research on Women's Health and Director of the Office of Research on Women's Health at the National Institutes of Health (NIH) in 2012. She is leading NIH's policy change initiative that requires scientists to include female animals and cells in preclinical research design.

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About the Faustman Lab

Under the direction of Denise Faustman, MD, PhD, the Immunobiology Laboratory at the Massachusetts General Hospital (MGH) has advanced the understanding of the role the human immune system plays in autoimmune diseases, cancer and transplantation. From basic research into turning the immune system on to fight cancer to a Phase II clinical trial to reverse type 1 diabetes, the lab conducts and then translates basic research in applications that help patients.

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“There’s something about the immune system in females that is more exuberant,” said Dr. Janine Clayton, director of the Office of Research on Women’s Health at the National Institutes of Health.

But there’s a high price, she added: Women are far more susceptible to autoimmune diseases, like rheumatoid arthritis and lupus, in which the immune system shifts into overdrive and attacks the body’s own organs and tissues.

Nearly 80 percent of those with autoimmune diseases are women, Dr. Clayton noted.