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Fauci says fast-spreading COVID variants BQ.1 and BQ.1.1 are ‘pretty troublesome’
"We've got to keep our eye out on these emerging variants," he said.
BY
CHLOE TAYLOR
Dr. Anthony Fauci, pictured in 2021, has said the new BQ.1 and BQ.1.1 COVID variants are "troublesome." Stefani Reynolds/POOL/AFP via Getty Images
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New COVID variants BQ.1 and BQ.1.1 are gaining traction in the U.S. at a “troublesome” rate, according to the White House’s top medical advisor Dr. Anthony Fauci.
In the week ending Oct. 15, BQ.1 and its offspring BQ.1.1 were closing in on the position of second most widely circulating COVID variant in the United States, according to projections from the Centers for Disease Control and Prevention (CDC).
On Friday, Fauci sounded the alarm on the new variants, which accounted for an estimated 11.4% of new COVID cases in the United States as of Oct. 15—double the proportion of infections they caused a week earlier.
“When you get variants like that, you look at what their rate of increase is as a relative proportion of the variants, and this has a pretty troublesome doubling time,” Fauci said in an interview with CBS News.
Alongside BQ.1 and BQ.1.1’s rapid infection rates, he voiced concern about the latter’s apparent ability to evade antibody treatments being used for patients at risk of developing severe COVID symptoms.
“That’s the reason why people are concerned about BQ.1.1, for the double reason of its doubling time and the fact that it seems to elude important monoclonal antibodies,” Fauci told CBS.
The BA.5 variant is currently still dominant in the U.S., accounting for around 68% of cases, while BA.4.6—which accounted for 12.2% of cases as of Oct. 15—is the second most common variant.
However, BQ.1 and BQ.1.1 have rapidly become more widespread in the U.S. in recent weeks, while BA.5 has been responsible for a smaller proportion of cases.
Despite the rise of the new variants, the latest data from the Centers for Disease Control and Prevention (CDC) paints a somewhat encouraging picture, with hospitalizations and new cases of the virus steadily declining over the past month.
Some epidemiologists and public health experts have warned, however, that Americans should brace for a resurgence of COVID infections in the coming fall and winter months—particularly with the Omicron variant continuing to evolve. Fauci backed those warnings during his interview with CBS.
“As much as you want to feel good about the fact that cases are down, hospitalizations are down, we don’t want to declare victory too prematurely,” he said. “And that’s the reason why we’ve got to keep our eye out on these emerging variants.”
However, he appeared optimistic that existing vaccines could offer some level of protection against BQ.1 and potentially suppress a surge in infections—particularly given the rollout of bivalent vaccines tailored specifically to the Omicron variant.
“The bad news is that there’s a new variant that’s emerging and that has qualities or characteristics that could evade some of the interventions we have,” Fauci told CBS. “But, the somewhat encouraging news is that it’s a BA.5 sublineage, so there is almost certainly going to be some cross protection that you can boost up.”
Dr. Anthony Fauci, director of the National Institute of Allergy and Infectious Diseases, testifies during the Senate Health, Education, Labor and Pensions Committee hearing titled Next Steps: The Road Ahead for the COVID-19 Response, in Dirksen Building on Thursday, November 4, 2021.
Tom Williams | CQ-Roll Call, Inc. | Getty Images
As winter inches closer, Dr. Fauci is sounding the alarm about a pair of "pretty troublesome" Covid variants.
The two descendants of omicron's BA.5 subvariant, called BQ.1 and BQ.1.1, both have dangerous "qualities or characteristics that could evade some of the interventions we have," Fauci told CBS News on Friday. The two sublineages are responsible for more than 10% of all current U.S. cases, according to the latest Centers for Disease Control and Prevention data — just one week after they weren't even significant enough to list.
There's no guarantee that the two strains will eventually overtake BA.5 as the dominant variant in the country. But if they do spread rapidly, they could threaten to reverse a nationwide decline in Covid cases, hospitalizations and deaths, leading Fauci to urge Americans against letting their guard down.
"As much as you want to feel good about the fact that cases are down, hospitalizations are down, we don't want to declare victory too prematurely," Fauci, the president's chief medical adviser, said. "And that's the reason why we've got to keep our eye out on these emerging variants."
BA.5 still makes up nearly 68% of all current U.S. cases. The new strains are responsible for almost 20% of cases in a region that includes the New York City metropolitan area, which many experts consider the area a bellwether for Covid waves — due to its dense population and high volume of incoming international travelers.
Fauci said the strains have a concerning "doubling time," referring to how quickly they spread. The U.K. Health Security Agency reported earlier this month that the strains even demonstrate a growth advantage over BA.5, which was considered the most contagious Covid strain to date.
BQ.1.1 is also particularly adept at dodging the protective antibodies you get from prior infection or vaccination, Fauci noted.
Scientists from Peking University in China published a study earlier this month that found BQ.1.1's ability to evade antibodies was "far exceeding" that of BA.5. The study, which has yet to be peer-reviewed, also found that BQ.1.1 was capable of evading immunity from a previous BA.5 infection and some antibody drugs, including Bebtelovimab and Evusheld.
Still, the fact that both strains come from BA.5 means the new omicron-specific booster shots likely provide some protection against them. Early clinical trial data suggests that the boosters work well: Pfizer's new shot generated a strong immune response against both omicron's BA.4 and BA.5 subvariants, the company reported last week.
"The somewhat encouraging news is that it's a BA.5 sublineage, so there are almost certainly going to be some cross-protection that you can boost up," Fauci said.
You can also protect yourself against the virus by wearing a mask in high-risk areas or situations. The CDC recommends masking indoors if you're in a county with a substantial or high-level spread of Covid.
Fauci, during an event with the USC Annenberg Center for Health Journalism earlier this month, said "it's entirely conceivable" that the U.S. will see enough of an uptick to encourage indoor masking nationwide again.
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