Nigeria reports poisonings from possible coronavirus drug & switches to treating those with autoimmune diseases with bcg obtained from japan relying on the work of g ristori, faustman dl, uspto.gov inventor search faustmsn, faustmanlab.org, while reminding white boys it is a slur to put a black box warning on azithromycin, better to do a bit of reading as with the case of chloramphenicol.
Curr Opin Immunol. 2018 Dec;55:89-96. doi: 10.1016/j.coi.2018.09.016. Epub 2018 Nov 15.
Bridging the gap between vaccination with Bacille Calmette-Guérin (BCG) and immunological tolerance: the cases of type 1 diabetes and multiple sclerosis.
Abstract
At the end of past century, when the prevailing view was that treatment of autoimmunity required immune suppression, experimental evidence suggested an approach of immune-stimulation such as with the BCG vaccine in type 1 diabetes (T1D) and multiple sclerosis (MS). Translating these basic studies into clinical trials, we showed the following: BCG harnessed the immune system to 'permanently' lower blood sugar, even in advanced T1D; BCG appeared to delay the disease progression in early MS; the effects were long-lasting (years after vaccination) in both diseases. The recently demonstrated capacity of BCG to boost glycolysis may explain both the improvement of metabolic indexes in T1D, and the more efficient generation of inducible regulatory T cells, which counteract the autoimmune attack and foster repair mechanisms.
By Jackie Salo
Nigeria on Sunday warned about cases of chloroquine poisoning after the anti-Malaria drug was hailed as a possible cure for coronavirus, according to a report.
Health officials in the West Afrian nation confirmed on Sunday that two people were hospitalized in Lagos for overdoses of the anti-Malaria drug, which President Trump has touted as a potential treatment, Bloomberg reported.
Nigeria’s Center for Disease Control cautioned citizens from self-medicating with the drug, which is still undergoing testing for safety and effectiveness.
“[The World Health Orgniazation] has NOT approved the use of chloroquine for #COVID19 management,” the agency wrote on Twitter. “Scientists are working hard to confirm the safety of several drugs for this disease.”
Oreoluwa Finnih, senior health assistant to the governor of Lagos, also told Nigerians “not to panic” and use the drug.
“Chloroquine is still in a testing phase in combination with other medication and not yet verified as a preventive treatment or curative option,” Finnih told Bloomberg News.
President Trump tweeted on Saturday that:”HYDROXYCHLOROQUINE & AZITHROMYCIN, taken together, have a real chance to be one of the biggest game changers in the history of medicine.”
He added that the FDA has “moved mountains” and that hopefully the treatment will be “put in use IMMEDIATELY.”
Nigeria has reported 27 cases of COVID-19 as it spreads to more than 300,000 people across the world, according to figures from John Hopkins University.
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