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Dr. Denise Faustman
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Watch Dr. Faustman's interview about the Phase I trial
Your donation will directly support our Phase II research.
Raised to date: $18.4 million
Our total need: $25.2 million.
Raised to date: $18.4 million
Our total need: $25.2 million.
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Interested in the Phase II Trial?
The Faustman Lab at Massachusetts General Hospital
Denise Faustman, MD, PhD, is Director of the Immunobiology
Laboratory at the Massachusetts General Hospital (MGH) and an Associate
Professor of Medicine at Harvard Medical School. Her current research
focuses on discovering and developing new treatments for type 1 diabetes
and other autoimmune diseases, including Crohn's disease, lupus,
scleroderma, rheumatoid arthritis, Sjögren's syndrome, and multiple
sclerosis. She is currently leading a human clinical trial program
testing the efficacy of the BCG vaccine for reversal of long-term type 1
diabetes. Positive results from the Phase I study were reported in 2012.Dr. Faustman's type 1 diabetes research has earned her notable awards such as the Oprah Achievement Award for “Top Health Breakthrough by a Female Scientist” (2005), the "Women in Science Award" from the American Medical Women’s Association and Wyeth Pharmaceutical Company for her contributions to autoimmune disease research (2006), and the Goldman Philanthropic Partnerships/Partnership for Cures “George and Judith Goldman Angel Award” for research to find an effective treatment for type 1 diabetes (2011). Her previous research accomplishments include the first scientific description of modifying donor tissue antigens to change their foreignness. This achievement earned her the prestigious National Institutes of Health and National Library of Medicine “Changing the Face of Medicine” Award (2003) as one of 300 American physicians (one of 35 in research) honored for seminal scientific achievements in the United States.
Dr. Faustman earned her MD and PhD from Washington University School of Medicine in St. Louis, Missouri, and completed her internship, residency, and fellowships in Internal Medicine and Endocrinology at the Massachusetts General Hospital in Boston, Massachusetts.
© 2014 Massachusetts General Hospital
Clinton Campaign Kickoffs Over the Years
How Hillary Rodham Clinton began her campaign for the United States Senate seat and for the presidency (twice).
By Quynhanh Do and Colin Archdeacon on Publish Date April 12, 2015.
Photo by Todd Heisler/The New York Times.
Ending two years of speculation and coy denials, Hillary Rodham Clinton
announced on Sunday that she would seek the presidency for a second
time, immediately establishing herself as the likely 2016 Democratic
nominee.
“I’m running for president,” she said with a smile near the end of a two-minute video released just after 3 p.m.
“Everyday
Americans need a champion. And I want to be that champion,” Mrs.
Clinton said. “So I’m hitting the road to earn your vote — because it’s
your time. And I hope you’ll join me on this journey.”
The
announcement came minutes after emails from John D. Podesta, Mrs.
Clinton’s campaign chairman, alerting donors and longtime Clinton
associates to her candidacy.
Mr. Podesta said that Mrs. Clinton would meet soon with voters in Iowa and host a formal kickoff event some time next month.
The
announcement effectively began what could be one of the least contested
races, without an incumbent, for the Democratic presidential nomination
in recent history — a stark contrast to the 2008 primaries, when Mrs.
Clinton, the early front-runner, ended up in a long and expensive battle
won by Barack Obama. It could also be the first time a woman captures a
major party’s nomination.
Hillary Clinton’s Announcement Video
On Sunday, Hillary Rodham Clinton
released a video featuring the stories of a diverse group of Americans
to announce that she will seek the presidency for a second time.
Publish Date April 12, 2015.
Regardless
of the outcome, Mrs. Clinton’s 2016 campaign will open a new chapter in
the extraordinary life of a public figure who has captivated and
polarized the country since her husband, former President Bill Clinton,
declared his intention to run for president in 1991. Mrs. Clinton was
the co-star of the Clinton administration, the only first lady ever
elected to the United States Senate and a globe-trotting diplomat who
surprised her party by serving dutifully under the president who
defeated her.
She
will embark on her latest — and perhaps last — bid for the White House
with nearly universal name recognition and a strong base of support,
particularly among women. But in a campaign that will inevitably be
about the future, Mrs. Clinton, 67, enters as a quintessential baby
boomer, associated with the 1990s and with the drama of the Bill Clinton
years.
This
campaign will begin on a small scale and build up to an effort likely
to cost more than any presidential bid waged before, with Mrs. Clinton’s
supporters and outside “super PACs”
looking to raise as much as $2.5 billion in a blitz of donations from
Democrats who overwhelmingly support her candidacy. Much of that
enthusiasm is tied to the chance to make history by electing a woman to
the presidency. But some, too, owes to the lack of compelling
alternatives in a party trying desperately to hold on to the White House
when Republicans control the House and the Senate.
Mrs.
Clinton’s declaration on Sunday is to be followed by a series of
intimate but critical campaign events in Iowa and New Hampshire. She
will use them to reintroduce herself to voters and begin to lay out the
central theme of her candidacy: improving the economic fortunes of the
middle class, with an emphasis on increasing wages and reducing income
inequality.
Paths to the Presidency: What Hillary Clinton Would Need to Do to Win
In
the video, she does not appear until after 90 seconds of images
featuring personal stories of others, each describing how they are
getting ready to start something new.
The
video prominently features a black couple expecting a child, a young
Asian-American woman, and two men who say they are getting married. It
also shows plenty of the white, working-class people who were crucial to
her previous White House bid and signals that she intends to make
helping the middle class and reducing income inequality major themes of
her campaign.
Near
the end of the video, Mrs. Clinton finally appears outside a suburban
home and says: “I’m getting ready to do something too. I’m running for
president.”
Her
return to the campaign trail this week offers her a fortuitous
circumstance: Tuesday is National Equal Pay Day, the point in the year
at which, on average, a woman’s pay for working in 2014 and 2015 would
equal a man’s pay just for 2014. Pay equity is an issue that Mrs.
Clinton’s candidacy will take up in earnest, along with others important
to many women, like paid family and medical leave, a higher minimum
wage and affordable access to child care.
Hillary Rodham Clinton’s Political Life
CreditAssociated Press
Unlike
in her 2008 campaign, when she played down gender and sought to show
she was tough enough to be president, Mrs. Clinton plans to highlight
that she is a grandmother and trumpet her chance to make history.
“Being
the first woman to run for president with a real chance of winning,
that’s a wild card, but potentially a net positive, particularly for
undecided women,” said Scott Keeter, director of survey research at the
Pew Research Center.
It
was not surprising that Mrs. Clinton chose to make her intentions
public in a video circulated on social media. Since she left the State
Department in early 2013, she has found a welcome outlet in Twitter,
which has allowed her to express her opinions in terse missives while
avoiding the news conferences that are likely to become a mainstay now
that she is a presidential candidate.
She
will also look for ways to demonstrate that, after more than three
decades in public life, she understands the ways of modern campaigns and
can appeal to younger voters. Mrs. Clinton’s 35-year-old campaign
manager, Robby Mook, known for exploiting technology, data and analytics
to win elections, has already dispatched field organizers to Iowa, New
Hampshire, Nevada and South Carolina.
Who Is Running for President (and Who’s Not)?
For
all the months of quiet and careful planning, however, her campaign’s
rollout did not come off as smoothly as envisioned. Rather than gliding
into the spotlight as an above-the-fray former secretary of state, Mrs.
Clinton entered the 2016 race in the midst of lingering questions about
her exclusive use of a private email address while at the State
Department and about donations from foreign countries to her family’s
philanthropic foundation.
Mr.
Podesta, the campaign chairman, assured donors that both controversies
would pass and that the momentum would shift as soon as Mrs. Clinton was
officially a candidate, according to a person involved in those
discussions.
Mrs.
Clinton will enter the race with a strong base of support: 81 percent
of Democrats said they would consider voting for her, according to a CBS News poll
conducted in February. That support dwarfs that of her potential rivals
for the nomination, including former Gov. Martin O’Malley of Maryland,
former Senator Jim Webb of Virginia and Senator Bernard Sanders, an
independent from Vermont who could run as a Democrat.
But
the roller coaster of a presidential campaign can erode even the most
seemingly certain advantages. Just over eight years ago, Mrs. Clinton
began that campaign with an email to supporters declaring that she was
“in to win.” That announcement began a downward trajectory in which she
went from being considered the inevitable nominee to finishing in third
place in the Iowa caucuses, behind Mr. Obama and John Edwards.
She
went on to pick up primary victories in crucial battleground states
like Ohio and Pennsylvania, but by then Mr. Obama had an edge in the
fight for delegates.
In her 2008 concession speech, Mrs. Clinton sought to energize the women who had supported her candidacy.
“Although
we weren’t able to shatter that highest, hardest glass ceiling this
time, thanks to you, it’s got about 18 million cracks in it,” she said.
“And the light is shining through like never before, filling us all with
the hope and the sure knowledge that the path will be a little easier
next time.”
This
time, Mrs. Clinton’s aides have signaled that she will take nothing for
granted and present herself as a more humble candidate, as unencumbered
by the trappings of power and celebrity as is possible for a
universally recognized former first lady, secretary of state and
presidential candidate.
There
may be little room for error, though, for Mrs. Clinton, who will begin
her campaign under the glare of intense media scrutiny and criticism
from a broad field of potential Republican opponents, including former
Gov. Jeb Bush of Florida, Gov. Scott Walker of Wisconsin, and Senators
Ted Cruz of Texas, Marco Rubio of Florida and Rand Paul of Kentucky —
all of whom will try to prove they are best positioned to defeat her.
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