Curr Opin Immunol. 2018 Dec;55:89-96. doi: 10.1016/j.coi.2018.09.016. Epub 2018 Nov 15.
Bridging the gap between vaccination with Bacille Calmette-Guérin (BCG) and immunological tolerance: the cases of type 1 diabetes and multiple sclerosis.
Abstract
At the end of past century, when the prevailing view was that treatment of autoimmunity required immune suppression, experimental evidence suggested an approach of immune-stimulation such as with the BCG vaccine in type 1 diabetes (T1D) and multiple sclerosis (MS). Translating these basic studies into clinical trials, we showed the following: BCG harnessed the immune system to 'permanently' lower blood sugar, even in advanced T1D; BCG appeared to delay the disease progression in early MS; the effects were long-lasting (years after vaccination) in both diseases. The recently demonstrated capacity of BCG to boost glycolysis may explain both the improvement of metabolic indexes in T1D, and the more efficient generation of inducible regulatory T cells, which counteract the autoimmune attack and foster repair mechanisms.
NYC Health Department gets graphic in coronavirus sex memo while proudly fucking people who may be easily, safely and inexpensive made better and more resistant to the corona virus.
Curr Opin Immunol. 2018 Dec;55:89-96. doi: 10.1016/j.coi.2018.09.016. Epub 2018 Nov 15.
Bridging the gap between vaccination with Bacille Calmette-Guérin (BCG) and immunological tolerance: the cases of type 1 diabetes and multiple sclerosis.
Abstract
At the end of past century, when the prevailing view was that treatment of autoimmunity required immune suppression, experimental evidence suggested an approach of immune-stimulation such as with the BCG vaccine in type 1 diabetes (T1D) and multiple sclerosis (MS). Translating these basic studies into clinical trials, we showed the following: BCG harnessed the immune system to 'permanently' lower blood sugar, even in advanced T1D; BCG appeared to delay the disease progression in early MS; the effects were long-lasting (years after vaccination) in both diseases. The recently demonstrated capacity of BCG to boost glycolysis may explain both the improvement of metabolic indexes in T1D, and the more efficient generation of inducible regulatory T cells, which counteract the autoimmune attack and foster repair mechanisms.
Sign up for our special edition newsletter to get a daily update on the coronavirus pandemic.
It’s not always better to love the one you’re self-isolating with.
The Department of Health issued guidance Saturday on ways to stay COVID-19-free when the birds and bees beckon amid the coronavirus pandemic.
First and foremost: self love is the best — and safest– kind of love.
“You are your safest sex partner,” the document reads. “Masturbation will not spread COVID-19, especially if you wash your hands (and any sex toys) with soap and water for at least 20 seconds before and after.”
But the agency did not entirely throw cold water on the idea of bumping uglies with a live, virus-free human.
“The next safest partner is someone you live with,” officials offered. “Having close contact– including sex — with a small circle of people helps prevent spreading COVID-19.
Anyone outside your household? Avoid.
And no “group sex” either, the agency said.
Horndogs who “usually” meet partners online should take a break — and make like it’s 2003.
“Video dates, sexting or chat rooms may be options for you,” the agency said.
Hairstylist Brian Magallones, 45, told The Post he appreciated the city’s advice — and agreed that it makes sense to give yourself a hand during the health crisis.
“Masturbating obviously is the safest thing to do,” he said. “That’s a no-brainer. And if you’re two people living in the same household, you’re already sharing germs.”
“Whatever you do in your personal life is your own business, but maybe this is not a good time to be having orgies outside of the house and bringing it all home,” he added.
Condoms and washing up are more important than ever, notes the memo, which was apparently removed, and then reappeared on the agency’s website later in the day.
“Our guidance is updated regularly,” a DOH spokesperson said.
No comments:
Post a Comment