Desmond Schatz, MD
Medical Director, UF Diabetes Institute
Dr. Schatz is Professor and Associate Chairman of Pediatrics, Medical Director of the UF Diabetes Institute, and Director of theUF Clinical Reserach Center. He has been involved in Type 1 diabetes research since the mid 80s and has published over 260 manuscripts, the majority related to the prediction, natural history, genetics, immunopathogenesis and prevention of the disease, as well as the management of children and adolescents with Type 1 diabetes. He is the Principal Investigator (PI) on several JDRF and NIH awards. He is PI on JDRF funded studies aimed at reversing Type 1 diabetes using autologous stem cells (cord blood) and is currently Principal Investigator of the University of Florida Clinical Center participating in the NIH-funded TrialNet. He serves as co-PI on a Program Project Grant looking at the immunopathogenesis of Type 1 diabetes, and also serves as co-PI for the NIH-funded international newborn genetic screening (TEDDY) program in North Central Florida. He has served in numerous capacities for the American Diabetes Association including his upcoming appointment as President of theAmerican Diabetes Association (ADA) beginning in 2016.
Research Overview
Up to 3 million Americans are stricken with type 1 diabetes, but the epidemic spans the globe and is rapidly worsening. The frequency of the disease has already soared five-fold in the past 50 years alone, and the costs to human health come into sharp focus. Diabetes is one of six leading causes of death in the United States, and the No. 1 cause of acquired blindness, kidney failure and non-traumatic amputation. It also fuels cardiovascular disease, the nation’s No. 1 killer, and accounts for more than $174 billion in health-care expenditures, with type 1 diabetes accounting for a disproportionate share of those costs. Dr Schatz’ research has focused on the prediction, natural history, genetics, immunopathogenesis and prevention of Type 1 diabetes, as well as the management of children and adolescents with Type 1 diabetes.
Current Clinical Trials
- PANDA Study
- TEDDY Study
- TrialNet Natural History Study
- TrialNet Oral Insulin Study
- TrialNet ATG-GCSF New Onset Study
Staff
Key Publications
Dr Schatz has published over 180 manuscripts and book chapters, the majority pertaining to the prediction, natural history, genetics, immunopathogenesis and prevention of the disease, as well as the management of children and adolescents with Type 1 diabetes. More…
Louis Philipson, MD, PhDProfessor of MedicineDirector, Kovler Diabetes Center
Louis Philipson, MD, PhD, is an endocrinologist and a leading world authority on diabetes mellitus. His clinical interests include type 1 diabetes, complicated type 2 diabetes, monogenic diabetes and hypoglycemia.
Recognized for unmatched expertise in the treatment of diabetes that is difficult to manage, Dr. Philipson's multisciplinary team frequently accepts referrals and provides consultations. Under his leadership, Kovler Diabetes Center has been recognized as a one of only seven National Institutes of Health (NIH) Diabetes Research and Training Centers in the U.S.
For more than 25 years, Dr. Philipson has tirelessly explored the biophysical, molecular and genetic aspects of insulin secretion, and the genetics of diabetes. He and his colleagues discovered rare insulin gene mutations that produce beta cell ER stress and, in turn, cause neonatal diabetes.
In addition, Dr. Philipson and his colleagues are among the nation's leading experts on monogenic diabetes, following more than 100 patients diagnosed with neonatal diabetes and many others with maturity onset diabetes of the young (MODY) type diabetes. He also serves as co-director of the Human Islet Transplantation project at the University of Chicago.
Dr. Philipson has served as principal investigator on numerous research projects. His work is widely published in biomedical journals, including the Proceedings of the National Academy of Sciences, Science, Nature, Diabetes, American Journal of Physiology and the Journal of Biological Chemistry.
As president of the Chicago/Northern Illinois board of the American Diabetes Association and a member of its National Board, he has been invited to speak and present at scientific research conferences and symposia worldwide. In addition, Dr. Philipson is the recipient of numerous awards including ADA Research Awards and the National Disease Research Interchange (NDRI) Outstanding Scientist Award. He was also named the 2011 recipient of the Samuel Eichold II Memorial Award for Contributions in Diabetes by the American College of Physicians.
Practice Locations
The University of Chicago Medicine
5841 S. Maryland Avenue Chicago, IL 60637
Duchossois Center for Advanced Medicine
5758 S. Maryland Avenue Chicago, IL 60637 Year Started Practice
1986
Board Certifications
Endocrine, Diabetes & Metabolism
Internal Medicine Medical School
The University of Chicago Pritzker School of Medicine
Internship, Residency and Fellowship
The University of Chicago Medicine
Additional Graduate Degree
PhD, University of Chicago (Biochemistry)
Memberships
American College of Physicians
American Diabetes Association Juvenile Diabetes Foundation International European Society for Study of Diabetes Language Spoken
English
Office PhoneOffice FaxOffice Postal Address
Louis Philipson, MD, PhD
The University of Chicago Medicine 5841 S. Maryland Avenue, MC 1027 Chicago, IL 60637 | Clinical Interests
Learn More About Dr. Philipson
Learn more about Dr. Philipson and his colleagues in the University of Chicago Kovler Diabetes Center.
Dr. Philipson is featured in"Journey to a Miracle: Freedom from Insulin," an independent documentary that focuses on the discovery of a groundbreaking discovery for monogenic diabetes.
Through his innovative research, Dr. Philipson uncovered a rare form of diabetes caused by a genetic mutation and developed a successful treatment.
Lilly Jaffe was diagnosed with a rare type of diabetes when she was just one month old. Dr. Philipson helped her to produce insulin, making Lilly the fourth such case to be treated in the United States.Read her story.
What Joey Knoop thought was just a cold turned out to be type 1 diabetes. After struggling with her blood sugar levels for year, Knoop was referred to Dr. Philipson and underwent an islet cell transplant to produce her own insulin. Read Joey’s story.
The University of Chicago Medicine's Science Life blog features Dr. Philipson in a video about the real human effects of a scientific breakthrough in diabetes care.
Dr. Philipson was featured in a video about diabetes research and patient care, which aired on Comcast's "Policy Makers."
Dr. Philipson, along with members of congress, was part of the team that declared an inaugural Diabetes Awareness Day in Illinois. Read the story.
Selected Publications
View a partial list of Dr. Philipson's publications through the National Library of Medicine's PubMed online database.
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